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Considering the developmental cost and the success rates associated with the new chemical entities, there is limited potential for developing novel synthetic retinoids.
As such, there has been an intriguing interest in discovering and developing novel multi-targeted PTK inhibitors, and most of them focused on small molecular entities.
The chemo- and radioresistance mechanisms of this tumor entity remain to be determined in order to develop novel treatment strategies.
Getting a variety of opinions helps companies develop novel perspectives.
And we must develop novel ways of fighting and exercising.
These challenges urged researchers to develop novel antitumor drugs.
And the third of the big three is what we call "novel entities".
It can detect entities that it has previously experienced and therefore reinforce existing associations, or detect novel entities necessitating a new association encoding.
The Center for Translational Pain Medicine (CTPM) represents a novel entity that is transforming the way that we diagnose and treat painful conditions.
In conclusion, we propose a novel entity of cellular demise, caspase-dependent regulated necrosis.
Diabetic hepatosclerosis (DH) is a novel entity that has recently been characterized by reviewing archived liver biopsies (1– 3).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com