The intervention was developed in alignment with the Down syndrome behavioral phenotype.
To address this need, an ObsRO measure based on caregiver report of observable RSV-associated symptoms in young children was developed in alignment with the US FDA guidance for use in a clinical trial setting.
Although the literature review identified numerous PROs used in patients with SLE, it identified a need for PROs developed in alignment with the FDA PRO Guidance to assess the fluctuations in symptoms and impacts experienced by patients with SLE.
Novel antiviral medications are in development to improve the clinical outcomes of RSV; however, no clinical outcome assessments (COAs) for RSV have been developed in alignment with the United States Food and Drug Administration patient-reported outcome guidance to assist in the evaluation of new therapies.
The GRCD was developed in alignment with the FDA PRO guidance following a rigorous and iterative process, thereby filling the need for a valid, reliable, and responsive measure of RSV symptom severity and change after treatment in infants and very young children.
Although the LupusPRO and LIT may have been developed in alignment with best measurement science, with content validity in the target population of interest and adequate measurement properties as required by the FDA, to the best of our knowledge, at the time of this study there was not comprehensive, publicly available, documented evidence that demonstrated this.
Today I'm amazed at how events have developed in alignment with and often behind the resources of social networks.
The Guidelines were developed in alignment with the UN Guiding Principles on Business and Human Rights and the Children's Rights and Business Principles.
Several large cohort studies of child health and development have been developed in close alignment with government in an attempt to more closely align science and policy translation.
Routines for performing within- and between-gel alignment were developed in-house, as follows.
If we started systematically developing athletes in alignment with the commonly touted values of elite sport – responsibility, leadership, fair play – then the effect on society could be immense.
