Sentence examples for developing defects from inspiring English sources

However, as our study did not include long-term follow-up of this former phenotype, we cannot exclude the possibility of gradually developing defects in the maintenance of cytoskeletal and junctional structures in adult cells.

Compared to adults, they have a ~20 times higher probability for developing defects in the urinary tract.

Importantly, both the craniofacial and midline brain anomalies can be consistently scored and their degree of severity correlated with concurrently developing defects within the CNS [ 70, 71].

Rho GTPase activities and cytosol membrane cycling are regulated by Rho GDP Dissociation Inhibitor (RhoGDI), and RhoGDI knockout mice develop defects in kidney structure and function that lead to death due to renal failure.

It assumes even higher significance in the case of structures constituting a nuclear reactor, wherein materials bombarded with neutrons develop defects that assist faster diffusion leading to greater plastic deformation.

To determine whether mice of this strain develop defects in mononuclear phagocyte system (MPS) function similar to those observed in patients, the pattern of sequestration of labeled immune complexes was compared 90 min after infusion into MRL-lpr/lpr and into normal B6D2 mice.

Second, almost all individuals with type 1 diabetes will over time develop defects in the hormonal counterregulatory defense against hypoglycemia.

Defects in glucagon responses to hypoglycaemia develop in Type 2 diabetes [ 12], and some patients develop defects in the other stress responses.

Individuals with this disease develop defects that are connected to loss of the physiological function of the UPR, including diabetes due to loss of β-cell function.

Indeed, C57Bl/6J, the most widely used mouse strain is defective for nicotinamide nucleotide transhydrogenase (Nnt) [ 28, 29], prompting a higher susceptibility to develop defects in insulin secretion and altered glucose homeostasis.

On the other hand, subjects with haplogroup T could be intrinsically prone to develop defects in the mitochondrial oxidative phosphorylation system, which, in turn, negatively affects the performance of mitochondrial ATP production [ 11].