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The role of dendritic cells (DCs) and their targeted manipulation in the body's response to implanted materials is an important and developing area of investigation, and a large component of the emerging field of biomaterials-based immune engineering.
And researchers in a developing area of investigation prefer not only to read what other researchers have written on topics close to theirs, but also to meet and interact with them face to face.
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To assist in developing appropriate areas of investigation and to formulate relevant research questions, we wished to initially identify which conditions in particular SAHP appears to be used for, and furthermore to obtain an overview of the study designs used.
Theoretical sampling was utilised, in that participants, parents and staff, were selected in order to inform our developing understanding of the area of investigation.
The engineering of antibody antigen interactions to reduce antibody-mediated buffering of soluble ligand has also developed into an active area of investigation, leading to novel antibody platforms designed to result in more effective antigen clearance.
The long-lasting health impact of the intrauterine environment on the developing foetus has become an area of investigation ever since Barker suggested the link for cardiovascular disease and type II diabetes [ 4].
A new area of investigation was developed that is now referred to as Computer-Aided Structure Elucidation (CASE).
In the sanitation sector, the focus was set on developing an analytical tool to improve planning procedures in the area of investigation, which can be applied in general to developing and newly emerging countries.
Moreover, the fact that exposure of neutrophilic cells to C. neoformans may stimulate secretion and that this stimulated secretion is under the control of SMS activity suggests involvement of PKD1 activity not only in constitutive but also in regulated secretion, an area of investigation not thoroughly developed yet.
The use of cognitive training interventions that focus on improving executive function by developing skills such as dual tasking is an active area of investigation for fall prevention [ 46, 47].
Developing practical clinical applications of these mechanotransduction pathways continues to be an important area of investigation in its relation to spinal pathology.
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