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The UKPDS demonstrated that the risk of developing, and the progression of, microvascular complications are substantially reduced with intensive blood glucose control (HbA1c approximately 7%) (UKPDS 1998a, b).
The UK Prospective Diabetes Study UKPDSS) and the Diabetes Control and Complications Trial (DCCT) demonstrated that the risk of developing and the progression of microvascular complications are substantially reduced with intensive blood glucose control (HbA1c approximately 7%) in both type 2 diabetes (UKPDS 1998a, b) and type 1 diabetes (DCCT 1993).
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This will allow assessment of the incidence of both newly developing DR and the progression of DR in this cohort of subjects with both type 1 and type 2 diabetes and will be the subject of a future report.
We found scarce, poor-quality, and heterogeneous data (different exposure comparisons) on effects of different amounts and forms of dietary fructose on risks of developing or the progression of NAFLD and on indexes of liver health in humans.
Together, we identified 6 observational studies that examined associations between dietary fructose or sucrose intake and risks of developing or the progression of NAFLD.
After stroke, the risk of developing dementia doubles, and the progression rate from mild cognitive impairment to dementia increases [ 11, 12].
Our results suggest that chromosomal instability develops during the progression process, and is rare in precursor lesions, as indicated by the less pronounced chromosomal changes in recurrent tumors.
Similar low levels can develop during the progression of arteriosclerosis.
HCC has been regarded as one of the major complications of BCS, and appears to develop chronically with the progression of BCS [ 10, 19].
Although HOX genes are known to play a role in the developing embryo and in the progression of adult glioblastoma, their role in regulating resistance to alkylating agents is unknown.
Programs have been developed to slow the progression of nosocomial infections.
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