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Priority number three indicates that many experts believed that it is important to include patient perspectives in developing adherence interventions.
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Secondly, the finding that true LTF increased with time on ART confirms the need to develop adherence support strategies adapted to long-term ART.
Patients or patient groups should help develop adherence interventions.
Videotapes will be analysed according to specific criteria (using a purposely developed adherence scale) for adherence to the manual.
Hence, specially developed adherence interventions can still make a relevant contribution, even in settings that already offer high-quality usual adherence care [ 18].
We selected new statin users to ensure a uniform study population, where previously developed adherence patterns to statin treatment would not influence the adherence estimate.
All sixteen experts that responded to the third proposition "Patient groups should (help to) develop adherence interventions" agree unanimously that focusing on patients is crucial to improve adherence.
The ultrastructural changes in cardiomyocytes of embryos from diabetic mice were characterized by the presence of swollen mitochondria and disorganized myofilaments with poorly developed adherence junctions and have been consistent with previous observation in mutant mice [ 36].
The corresponding experts reviewed each intervention element, either identified via the literature search or during the patient interviews, and its relevance and suitability were evaluated for inclusion or exclusion from the newly developed adherence-enhancing intervention TTOP.
Developing effective adherence interventions requires better analytic models of adherence practice.
For the older regimens mainly used in the developing world, adherence poorer than 90-95% is likely to result in the development of resistant virus[ 18- 23], while treatment interruptions can also encourage resistance[ 24].
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