The earlier finding that ectopic expression of BCL11B in HeLa cells caused cell cycle retardation inspired the authors to develop a hypothesis of unscheduled proliferation as a primary cause of cell death in Bcl11b-depleted cells.
Our new results in Figure 8 suggest that Ephialtitidae is the sister group to all other Apocrita (Kuafuidae + (Orussoidae + ((Stephanidae + Evanioidae) + (Ceraphronmorpha + (Proctotrupomorpha + (Ichneumonomorpha + Vespomorpha))))), which add more details to the understanding and made possible to develop a hypothesis of the early evolution of higher Hymenoptera.
The authors then develop a hypothesis on the possible existence of cytokinin riboswitches.
The present study on one hand explains the most important elements of a RCT: developing a hypothesis, internal validity, relevance of the results and external validity.
The main disagreements concerned the question of whether the process of developing a hypothesis (the "colligation" in Whewell's terms) is or is not a part of discovery proper, and if it is, whether and how this process is guided by rules.
This model was used to develop an hypothesis of the selective mechanism explaining the evolution of large eyes in the giant squid [ 1], concluding that large eyes perform best in detecting large luminous objects in the deep sea.
As was noted in the editorial accompanying the proceedings from the 1989 National Conference on Clustering of Health Events, the unique aspect of a cancer cluster investigation is the reactive nature of the study, often from "data toward a hypothesis, in stark contrast to the scientific method of developing a hypothesis first and then gathering data to confirm or deny it" (Anonymous, 1990).
Taking into account the results obtained using the combined study of the near and far electric fields recorded in water and equivalent electromotive forces recorded when the fish is in the air we developed an hypothesis on how the different generators of each fish are represented in the far field for each species (Fig. 8).
The format for each case discussion is to identify the cues, the facts of the case in terms of signs, symptoms, and other pertinent data; develop a hypothesis list of basic science principles and concepts that explain as many of the cues as possible; and a list of learning issues that will guide students in independent learning activities prior to their next PBL session.
Building on the data from this project, Dr. Hill and her research student developed a hypothesis that some of the novel antibiotic-resistant bacteria also might be producers of antimicrobial compounds themselves.
