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The separation of naratriptan hydrochloride and its related products (impurities and degradation products) was obtained by developing a gradient high-performance liquid chromatography method with diode-array detector (HPLC-DAD).
Upon developing a gradient of 0.1% TFA against and acetonitrile, ET peptides of different lengths are resolved in time.
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The researchers then altered the voices further, tweaking pitch and tone, and developed a gradient of nine voices from least to most trustworthy.
For this purpose, we developed a gradient method to load and unload CPAs with the intention of minimizing sudden changes in osmolarity and thereby avoiding osmotic stress in the slices in comparison with the commonly used step-wise loading/unloading approach.
We also developed a gradient descent approach to achieve the best compromise between the distorted image and the image reconstructed using sparse representation.
As the tumor grows, its cells consume substrate and the substrate concentration develops a gradient, the concentration increasing in the radial direction away from the tumor centroid.
This creates a gradient, an exploitable structure, which allows future work to develop a gradient descent strategy, which would be an improvement over current hill climbing techniques.
In both cases, (suspension and agar plated) larger U-87 MG spheroids develop a gradient of proliferation as measured by Ki-67 staining [ 10] and a more intense glucose transporter 1 (GLUT-1) staining that correlates with tumor hypoxia [ 38].
Median LV outflow gradient increased from 11 (IQR 7 31) to 27 (IQR 16 98) mm Hg on exercise; 15 patients (20%) without obstruction at rest developed a gradient ≥30 mm Hg on exercise and 18 (24%) had an increase in outflow gradient ≥50 mm Hg.
This paper develops a gradient-based optimum block adaptive ICA algorithm (OBA/ICA) that combines the advantages of the two algorithms.
For flux computation, we developed a gradient-based hybrid optimization algorithm.
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