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However, higher hopes are pinned on inoculating the population: Scientists in Brazil are in the final stages of developing a dengue vaccine that could immunize humans against the four strains commonly found in the country.
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The purpose of this study was to develop a dengue scoring system using a three-stage process, which may be used as a guidance tool for the early diagnosis of dengue fever.
Recently, the AG129 mice were used to develop a dengue hemorrhagic fever disease model that manifests vascular leak, thus, more closely resembling the human condition [8].
Efforts to develop a dengue vaccine have been hampered by lack of appropriate animal models.
Our previous studies in southern coastal Ecuador demonstrated the potential to develop a dengue EWS that incorporates climate and non-climate information.
Previous studies in southern coastal Ecuador have demonstrated the potential to develop a dengue early warning system (EWS) that incorporates climate and non-climate information.
This study contributes to ongoing efforts by INAMHI and the MSP of Ecuador to develop a dengue prediction model and early warning system.
Stakes for developing an effective dengue vaccine are high.
In 2004, for example, the pharmaceutical company Novartis opened an Institute for Tropical Disease here, with a specific focus on developing a treatment for dengue.
French drugs giant Sanofi is developing a vaccine for dengue fever, and GSK's malaria vaccine – in the works for 30 years – is in the hands of regulators with a verdict due next year.
In summary, our study highlights single measurement of CRP as a potential useful and simple biomarker to identify patients who are at risk for developing a more severe dengue illness and to help triage patients requiring hospital care.
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