12 Children with moderate or severe encephalopathy face an elevated risk of dying or developing cerebral palsy, although they may also develop without complications.
For example, one 20- to 21.5-month-old CR-then-AL-fed female delivered 7 offspring, of which 6 survived and developed without any apparent complications (female #5, Fig. 4D).
Those classified as having no or minor encephalopathy were assumed to develop without any complications due to oxygen deficiency but may still face a risk of developing cerebral palsy due to other causes.
In patients who develop a complication after remission of the symptoms that led to the initial diagnosis of CD (type B cases), the prognosis is better than in patients in whom the complication of CD developed without the initial symptoms ever going into remission (type A cases).
Three previously healthy toddlers developed cellulitis (recovered without complications), meningitis (bilateral sensorineural deafness developed), and pneumonia (died).
Of the 10 rats with unilateral 6-OHDA lesions and chronic L-DOPA treatment, 8 (80%) developed dyskinetic behaviors during the 21 days of treatment (Friedman test S = 20.45, p<0.0001), whereas none of the animals treated with saline, or given sham lesions with or without L-DOPA treatment, developed motor complications (Figure 1A).
In the 14 cases without a wound leak, five developed wound complications (p = 0.06, Fisher's exact test) either from delayed wound-healing or pin-site infections.
Reducing the risk for gastrointestinal complications requires a thorough understanding of potential complications and underlying predisposing risk factors, which is a particularly important consideration in light of the fact that many individuals develop complications without antecedent warning signs or symptoms.
In the questionnaire study, the intervention group reported significantly higher levels of self-efficacy in relation to managing a patient who was at high risk of developing complications without using antibiotics.
The group of patients who developed ICU complications had a longer length of ED stay compared to those without complications (349 vs. 209 minutes, P = 0.002).
Among the patients who did not have complication at discharge, 20% subsequently developed complications during the first year; whereas only 7.6% were without any complication.
