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It will greatly facilitate the development of hESC-based therapy if new effective approaches can be developed to induce immune tolerance to hESC-derived allogeneic cells without long-term systemic immune suppression.
Additional strategies have been developed to induce Cre expression specifically in activated, collagen-producing HSCs, even in an inducible manner.
A highly efficient method was then developed to induce these human iPSCs into proliferative SMCs.
A post-signal processing model is developed to induce pressure and shear stresses, respectively.
To enable the use of treated soils in railways infrastructures a specific test was developed to induce biaxial tension.
An eccentric shoulder exercise was developed to induce DOMS on neck/shoulder muscles using a specially designed dynamometer.
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Indeed, GM-CSF-encoding VV or herpes virus has been developed to effectively induce tumor regression [ 38, 39].
Radiofrequency (RF), non-contact, selective-field device Vanquish® has been developed to selectively induce deep fat tissue heating to reduce waist circumference.
Most of the successful vaccines developed to date induce a long-lasting protective humoral adaptive immune response, eliciting the production of neutralizing or opsonizing antibodies [ 53].
Human cell-based bioassays have been developed to evaluate induced androgenic and estrogenic activities of chemical compounds.
Another group of methods have been developed to address errors induced by spatial modeling of exposures or spatial autocorrelation and have shown promise in simulation studies [ 17, 57- 59].
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