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Conversely, regions such as the thalamus or globus pallidus containing grey matter developed heterogeneity of color with regional variation.
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The identification of common targets upon which tumours rely to sustain and develop heterogeneity is now an experimentally tractable problem in cancer medicine.
To understand how heterogeneity is produced and how it propagates through the population, we developed a heterogeneity network.
Furthermore, the implanted tumor cells may even harbor different clones and/or develop tumor heterogeneity.
In the course of developing the heterogeneity algorithm, the test matrices were mathematically designed so they could be used to confirm the structure and performance of the algorithm.
In a recent study, a mycobacterial population of M. smegmatis was shown to develop phenotypic heterogeneity under nutrient depletion.
Detailed immunohistochemistry (IHC) analyses of such tumors showed that during their expansion in mice, initially pure ER+PR+ cells develop cellular heterogeneity.
Through these steps, and after formation of a metastasis, tumors in advanced stages develop biological heterogeneity and increased radioresistance before and during SBRT.
This observation led Tryziack and co-workers to analyze microcirculation images to develop a heterogeneity index to quantify this type of microcirculatory alteration [ 25].
No causality relationship is found for pollution and income that can be due to the different stages of economic development of emerging, former-transition, and developed economies, implying heterogeneity in their environmental protection policies.
A novel non-intrusive image analysis approach was designed and developed for quantifying heterogeneity in vegetation growth.
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