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Nanostructured lipid carriers (NLC) have been developed for sustained release of triamcinolone acetonide (TA), a corticosteroid commonly indicated for macular edema, neovascularization, and other ocular inflammatory disorders.
A unique starch-based confection containing freeze-dried strawberries was developed for sustained, targeted phytochemical release to the oral mucosa for use in future chemoprevention trials.
More recently, gel-based formulations are being widely developed for sustained delivery of HIV microbicides and mucosal vaccines.
(26) In this study, mucoadhesive, site-retentive RSV formulations, comprising multipolymeric components, have been developed for sustained vaginal delivery of therapeutics agents.
Of the many porous materials being developed for sustained release drug delivery systems, electrochemically etched porous silicon (pSi) is an attractive candidate because of its highly tunable nanostructure (micro- to macroporous), chemically modifiable surface, biocompatibility, and biodegradability.
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To identify and describe the formats that are not promising for long-term sustainability, and develop strategies for sustaining the content they contain.
To identify and describe the formats that are promising for long-term sustainability, and develop strategies for sustaining these formats including recommendations pertaining to the tools and documentation needed for their management.
To do so, hummingbirds developed the capacity for sustained hovering by creating power strokes on both the downstroke and the backstroke of wing action.
Understanding these drivers is essential in developing strategies for sustaining native biodiversity in agricultural landscapes into the future.
- Therefore, a subject bearing a CYP27B1 polymorphism may be prone to develop autoimmunity for sustaining concentrations of 1,25(OH)2D3 within the immune cells that are insufficient for full intracrine and paracrine tolerogenic effects of this powerful steroid molecule.
The results of our study indicate that diagnosis with acute/early HIV infection is likely to promote some degree of short-term behavior change, but efforts will be needed to help people develop strategies for sustaining these changes.
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