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Genome-wide mapping of the in vivo DNA-binding sites of transcription factors or other DNA-binding proteins either by Chromatin Immunoprecipitation coupled with microarray (ChIP-chip) or by the recently developed ChIP coupled with high-throughput sequencing (ChIP-seq) method have become widely used techniques in protein DNA interaction research.
The efficiency of the developed chip breaking system was investigated relative to different feed rates, machining speeds, and cutting depth by using cementite carbide inserts under dry cutting conditions.
Another result, coming from embryonic gene expression studies with recently developed chip technologies, was that one and the same gene product can be expressed at different stages of development and in different tissues, and that it can be implicated in quite different metabolic and cellular functions.
MD developed chip design and revised the manuscript.
These findings may be seen as confirming the validity of the previously developed CHIP prediction rule [ 1].
This chip was similar to a previously developed chip, which was used for a miniaturized enzymatic on-line BCD utilizing mass spectrometry as readout [ 19].
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And technology is evolving rapidly: start-up companies have developed chips as small as postage stamps that can analyze thousands of genes at a time or perform complex chemical analyses.
Others like mPowa also have developed chip-and-PIN readers to work alongside their mobile apps; its solution is certified to PCI (Payment Card Industry) 1 while Payleven describes its as 3.1.
An Israeli outfit called On Track Innovations has developed chips that carry biographical and biometric data to be inserted in ID documents.
However, just as genotyping at 384 loci has become routine, the number of loci on newly developed chips has risen to 44000, and is soon to reach 1, 000,000 loci ([Tung et al. 2011]).
We applied expression profiling to identify the response program of PC3 cells expressing the AR (PC3-AR) under different growth conditions (i.e. with or without androgens and at different concentration of androgens) and then applied the newly developed ChIP-seq technology to identify the AR binding regions in the PC3 cancer genome.
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