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We have developed a modality to bring about treatment-induced alterations in the tumor microenvironment by employing the synergistic effects between two drugs.
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To overcome the challenges of retinal imaging with all types of eyes in high resolution and develop a modality that is suitable for clinical use seems to require a better understanding of the visual processes, especially the function and importance of eye movements in vision.
Barton and associates [ 7, 8] also developed a dual-modality miniature endoscope and imaged the gastrointestinal tract in a murine model of colon cancer.
We have developed a dual-modality OCT/FLIM imaging system to explore the hypothesis that a more complete survey of the optical response would significantly improve the diagnostic power for the early detection of pathological conditions.
We have developed a dual-modality system, incorporating optical coherence tomography (OCT) and fluorescence lifetime imaging microscopy (FLIM), that is capable of simultaneously characterizing the 3-D tissue morphology and its biochemical composition.
Therefore, we developed a high resolution modality consistent with the binding dynamics observed within adhesions using time correlation of TIRF image time series.
To assess whether this approach could be adapted to the repeated, sequential monitoring of individual animals, specifically under conditions of a partial loss of beta cells such as is expected in type 2 diabetic patients [ 31], we developed a new, dual modality nanoparticle probe that targets the GLP-1r and that is suitable for both fluorescence and MRI.
Optical imaging developed into a modality which enables the visualization and quantification of all kinds of cellular processes and cancerous cell growth in small animals.
A possible solution to the medical imaging problems detailed in the WHO reports is to develop a different modality for medical imaging.
To this background we developed a new improved imaging modality for observation of the microcirculation called sidestream dark-field (SDF) imaging [ 49].
In comparison to previous reports, we wanted to go a step further developing a dual-modality linker using the previously described 18F/19F exchange reaction with the BODIPY-Fl dye which can be site-specifically conjugated to biomarkers in the second step.
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CEO of Professional Science Editing for Scientists @ prosciediting.com