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The repeatedly exposed animal cannot develop tolerance to food antigens and exhibits autoimmune deviations.
Repeatedly exposed young animals do not develop tolerance to food antigens and exhibit autoimmune deviations.
"People develop tolerance to caffeine within a few days, so the effects cannot be extrapolated to the long term.
Nevertheless, plants can develop tolerance to growth at high temperatures through the accumulation of heat shock proteins in the thylakoid membranes44.
Cells respond, adapt and may develop tolerance to chemicals by mechanisms only partially explored, especially for multiple simultaneous stresses.
Doctors often increase opioid dosages because patients can adjust, or develop tolerance, to the drugs and need greater amounts to get the same effect.
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The restriction in part stems from concerns that patients will develop tolerances to the drug or will abuse them.
The first one, known as the hygiene hypothesis postulates that a more sanitary childhood environment should prevent the host from developing tolerance to organisms that may present later in life, with the subsequent development of CD lesions [41].
The lead researcher, Dr. Asokumar Buvanendran of Rush University Medical Center in Chicago, said regular users of opioids like morphine might have developed tolerance to its side effects.
Her doctor put her on OxyContin and methadone and then raised the dosage every six months or so after she developed tolerance to the lower dosage.
P rats developed tolerance to the attenuating effects of TA-0910 on alcohol intake within 3-5 days.
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