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It also can be applied to develop screening systems for therapeutic antibodies and/or compounds.
Since various membrane proteins and their oligomeric complexes can be displayed on BV in the native form, this BV display system should prove highly useful in the search for natural ligands or to develop screening systems for therapeutic antibodies and/or compounds.
With enough effort, it probably would be possible to develop Screening Set STRPs with higher average heterozygosities for populations such as Native Americans, but the practicality of such an undertaking is uncertain.
Such data on toxicologically relevant in vitro end points can be used as toxicity-based triggers to assist in decision making (Reif et al. 2010), as predictive surrogates for in vivo toxicity (Martin et al. 2010; Zhu et al. 2008), to generate testable hypotheses on the mechanisms of toxicity (Xia et al. 2009), and to develop screening assays based on pathway perturbations.
Dr. John S. O'Brien, who identified the gene that causes Tay-Sachs disease and helped develop screening tests for the rare but fatal disorder among infants, died on Feb. 1 at his home in San Diego.
"I'm a radiation phobe — I'll come right out and say this," said Dr. Rhodes, an internist at the Mayo Clinic who is doing research to develop screening technologies that require less radiation exposure to the patient.
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Thus, this investigation has concentrated in optimizing the fine size separation performance of a newly developed screening technology, known as the Pansep Screen.
Previous authors have developed screening instruments aimed at identifying high risk populations of older adults.
The newly developed screening plasmid pBJGMM001 permits greater coverage of food and feed products that may contain GM ingredients.
The U.S. EPA has used some of the data in its now obsolete Chemical Assessment and Management Program to develop screening-level hazard, exposure, and risk characterizations for certain HPV chemicals (U.S. EPA 2012a).
She has lobbied the Virginia legislature in support of developing screening programs for all pregnant women.
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