The use of the cmRCT design, the development of self-guided online interventions, and partnerships with patient organizations will allow SPIN to develop, rigorously test, and effectively disseminate psychosocial and rehabilitation interventions for people with scleroderma.
Concentrated efforts to develop rigorously designed bioprocesses with a greater emphasis placed on QbD will continue to enhance process understanding with respects to defining critical quality attributes and identifying key process variables that must be controlled.
To achieve the desired levels of reliability, mechanisms for detecting and handling errors should be developed rigorously or formally.
To obtain an optimal control law, the proposed approach is developed rigorously by using Hamilton Jacobi Bellman (HJB) equation, Lyapunov technique, and inverse optimality, and hence guarantees that the chaotic drive network synchronizes with the chaotic response network influenced by uncertain noise signals.
Thirdly, based on the relationship properties between the normalizing signal and all the signals in the closed-loop system and on some important mathematical tools on discrete-time systems, as in the continuous-time case, a systematic stability and convergence analysis approach to the discrete indirect MRAC scheme is developed rigorously.
In addition, in benchmarking empirical measurements on PPINs we used null models generated via recently developed rigorously unbiased algorithms.
Developing rigorously controlled reagents, technical methods and appropriate interpretation requires adequate resources and to date this has rarely been forthcoming.
Although healthcare worker training has long been accepted as an integral part of disaster preparedness, traditional training practices have not been systematically developed, rigorously examined or objectively tested.
In the 1910s, TCI undertook a comprehensive program to stabilize its labor force, excluding prison laborers, by developing rigorously-planned "model villages", thereby improving worker health, welfare and loyalty.
But if the aid could be used to develop and rigorously test programs like Progresa, the knowledge garnered could stimulate more development aid and encourage poor countries to pursue more effective policies.
Capital requirements should be strengthened, particularly for complex financial instruments like some of the mortgage securities that led to our current crisis.We must develop and rigorously manage liquidity risks.
