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Cox regression models (univariable and multivariable) were used to develop predictor models using all baseline variables.
A second neoadjuvant study was recently published using cDNA arrays to develop predictor for paclitaxel, fluorouracil, doxorubicin, and cyclophosphamide, involving 24 samples.
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A second neoadjuvant study was recently published with the use of cDNA arrays to develop predictors for paclitaxel, fluorouracil, doxorubicin, and cyclophosphamide, involving 24 samples.
Those data could be used to develop predictors for the broader population based on traits that are recorded in most herds (e.g. Cole et al., 2014).
Our previous work has made use of expression data to develop predictors of tumor outcome, activation of various cell signaling pathways, and response to targeted therapies.
As ever-larger clinical data sets become available for gene-expression analysis, the DASL assay using FFPE tissue will help develop predictors of molecular class-specific prognosis and treatment response.
We do not have data on regional body composition or blood pressure, so we were unable to assess the risk of metabolic syndrome or coronary heart disease or develop predictors for the same in this population.
Objectives This study was used to determine the effectiveness of the Renal Angina Index as a developing predictor of AKI in 3 days.
In particular, developing predictors based on multiple SH2 domain probes is likely to improve the discriminating power of SH2 profiling, and is therefore a high priority for future studies.
Other possible aims with pre-specified groups include demonstrating global differences between groups using multivariate analysis (without identifying individual genes that are differentially expressed), and developing predictors of group membership (Golub et al, 1999; Hedenfalk et al, 2001).
Another advantage of the split sample method, particularly in large collaborative studies in which multiple groups will be developing predictors, is that the test set can be kept under "lock and key" by a honest broker [ 4].
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