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In our study, obese women are more likely to develop offspring macrosomia, with 1.7-fold risk increase compared to normal weight women, thereby confirming the results of previous published studies [ 14, 15].
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Specifically, research models of over-nutrition have demonstrated that early dietary insults can alter gene expression and promote atherosclerotic disease development in the developing offspring [ 24].
Males and females often have different requirements during early development, leading to sex-specific interactions between developing offspring.
Among the live-bearing species are some that have developed a complex placenta for transferring nutrients directly to the developing offspring.
The moths actively pollinate to ensure a food source for their developing offspring.
These changes may, in turn, cloud interpretations of spaceflight effects on developing offspring.
This study provides direct evidence that PPS modifies brain architecture in developing offspring, including dendritic length, cell complexity, and spine density.
Protection of developing offspring from the potential adverse effects of in utero exposures is an important aspect of the safety profile for medicines, chemicals and physical agents.
This mechanism is also applicable for cancer stem cells where mutations accumulate over time, produces the long-term effect of exposure to carcinogenic agents and grants drug resistance to their abnormally developing offspring.
The testing strategy for drugs includes an evaluation of all of these phases except that there is no requirement to expose the developing offspring from weaning through puberty to sexual maturity.
In the final stages of pregnancy, dominant females provide their developing offspring with higher androgen levels than lower-ranking mothers do.
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CEO of Professional Science Editing for Scientists @ prosciediting.com