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Moving forward, we harness these understandings to develop novel therapeutics regimens, including cell transplantation, activation of endogenous cells, and therapeutic interventions targeting the microenvironment and signaling pathways.
Putative biomarkers have also emerged as treatment targets, with the potential to develop novel therapeutics.
Naturally occurring and genetically engineered animal models afford a means to investigate adrenocortical tumorigenesis and to develop novel therapeutics.
Our goal is to understand the molecular mechanisms by which rapamycin beneficially affects SMC phenotype, in order to develop novel therapeutics.
Nevertheless, the increasing load and the still suboptimal outcome for patients with cardiac dysfunction underlines the relevance of continuous research to develop novel therapeutics for these diseases.
In biomedical research there is an ongoing demand for new technologies, which help to elucidate disease mechanisms and provide the basis to develop novel therapeutics.
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Since joining Sangamo BioSciences he has been working on developing novel therapeutics based on engineered ZFPs.
Nakagawa, T. Strategies for developing novel therapeutics for sensorineural hearing loss.
The program conducts trials that provide proof of mechanism, proof of principle, and proof of concept early in the process of developing novel therapeutics.
His keen interest in developing novel therapeutics in biomedicine drew him to the Spiegel lab (Yale Chemistry), where he was involved in advancing and translating some of the cancer therapeutics and blood storage discoveries in the lab, into the clinic.
These insights into the molecular control of bone remodelling raise the possibility of developing novel therapeutics for bone diseases designed to target specific aspects of this process.
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