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There is a need to develop novel derivatives with an improved spectrum of activity and higher sensitivity against pathogenic bacteria.
In order to develop novel derivatives of oridonin with improved potency, a series of nitric oxide (NO -releasing oridoNO -releasinges were synthesized by coridoninderivativesolates were oridonin and itsynthesizedesized analogues.
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We have recently developed novel derivatives, that carry three cationic charges only.
In order to develop novel electrochromic materials, four vinylbipyridinium derivatives (VBPDs) were synthesized.
In order to develop novel long-acting GLP-1 derivatives, a peptide hybrid (1a) from human GLP-1 and Xenopus GLP-1 discovered in our previous research was selected as the lead compound.
The reported data is expected to be useful for developing novel pyrazolone derivatives as lead compounds in the management of diabetic complications.
Thus, the interest in developing novel platinum derivatives as well as clinically applicable strategies to increase the sensitivity of human neoplasms to CDDP remains high.
In an effort to develop novel potent antitubercular drugs, thirty-one oridonin derivatives were designed and prepared.
In this context, it is still desirable to develop novel organic gain media based on fluorine derivatives with extremely low thresholds and excellent lasing properties.
In an attempt to develop novel antifungal agents, our previously synthesized phenoxyalkylpiperazine triazole derivatives were used as lead structures for further optimization.
In an effort to develop novel small molecule PTP1B inhibitors, a series of bromophenol derivatives were designed, synthesized and evaluated in vitro and in vivo.
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