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It's not going to happen tomorrow, nor even in the next year – but the short list of reasons to develop natively is growing shorter each day.
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We've found that developing natively works best for us and, understandably, most of my advice is colored in the light of this experience.
To the best of our knowledge, none of the available fuzzy shells is natively developed for the Arabic language.
GridGain systems develop (open source) cloud applications that facilitate the development of highly scalable applications that work natively on any managed infrastructure (from a single Android device to large grids or clouds).
Instead of providing a transitional HTTP/CCN transforming gateway or proxy, we design and develop the first practical CCN-enabled web server (called CCNxTomcat) based on open source Apache Tomcat and the CCNx library to natively support CCN-based web applications.
To make the DBMS available in any OS environment, we developed an SQLite JDBC connection library, which packs natively compiled SQLite binaries (SQLite is written in C) for operating systems such as Windows, Mac OS and Linux.
In order to overcome this problem it is proposed that an embedded processor capable of natively executing the CLI instruction set be developed.
In conclusion, we have developed an improved nondenaturing purification protocol that demonstrates significant conformational differences between natively- and non-natively purified RNA.
Instead of providing a browser add-on or HTTP NDN proxy/gateway, we designed and developed a complete NDNBrowser based on open source WebKit to natively support NDN-based web applications in the web browser kernel.
To mimic the palmitoylation of endogenous Cav3, we developed a generally applicable approach to covalently attached thioalkyl chains at natively modified cysteine residues.
Valve announced in July 2012 that it was developing a Steam client for Linux and modifying the Source engine to work natively on Linux, based on the Ubuntu distribution.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com