Elucidating the molecular mechanism by which mPTP opening is regulated during aging would provide an important clue for developing modalities to reduce the incidence of heart failure in elderly patients.
For newly developed modalities, crowd-sourcing provides a means to a rapid consensus as to the best collection and analysis methodologies.
Ultrasound radio frequency (RF) technology is a newly developed modality used for evaluating vascular elasticity of the carotid artery; the measurement of artery elasticity is based on the monitoring of RF signals transmitted by ultrasound.
In pursuit to understand and develop treatment modalities for orthodontically induced root resorption, the ability to manipulate cells within their natural extracellular matrix in a three dimensional organotypic model is invaluable.
A better understanding of RhoA/ROCK1 regulation on leukaemia cells could be contributing to develop new modalities for treating haematologic malignancies.
Considerable effort is needed, however, to determine the exact kind of expertise needed for specific cases and to identify specialists and develop the modalities required for effective sharing of this expertise between countries.
Physicians and scientists are now turning to the fields of tissue engineering and regenerative medicine to develop alternative treatment modalities for ESRD.
To develop novel treatment modalities for this fatal disease, new devices must be tested on an ideal animal model before performing clinical trials in humans.
In addition, pertinent future challenges and opportunities in the development of intravitreal implantable devices is discussed and explores their application in clinical ophthalmic science to develop innovative therapeutic modalities for the treatment of various posterior segment eye diseases.
This review article provides a concise incursion into the current and future applications of nano-enabled drug delivery systems for the treatment of NDs, in particular Alzheimer's and Parkinson's diseases, and explores the application of nanotechnology in clinical neuroscience to develop innovative therapeutic modalities for the treatment of NDs.
