Sentence examples for develop hallmark from inspiring English sources

Significantly, recent evidence suggests that mice genetically deficient in TLR5, a component of the innate immune system that is expressed in the gut mucosa and that helps defend against infection, exhibit hyperphagia and develop hallmark features of metabolic syndrome, including hyperlipidemia, hypertension, insulin resistance and increased adiposity [ 97].

Zebrafish expressing mutant sod1 develop hallmark features of ALS commonly associated with both murine models and the human disease 13 (a comparison of pathophysiological changes in our sod1 zebrafish model, SOD1 mouse models, and human ALS is summarized in Table 2).

Other evidences showed that the TLR5 receptor was conversely protecting against metabolic syndrome since mice genetically deficient in TLR5 exhibited hyperphagia and developed hallmark features of metabolic syndrome [ 89].

Even before the brains of human patients develop a hallmark of the disease--the protein clumps called plaques--their memories deteriorate and they lose neurons.

And, during this time, The Shore Club continued to develop their hallmark oceanfront villas – six deluxe oases that enjoy all hotel amenities, while secluded in their own private alcoves dotted along the shore.

By age 40, the brains of all people with Down syndrome develop the hallmark plaques and tangles of Alzheimer's and other signs of brain atrophy, autopsy studies have found.

As stated in the Introduction, these derivatives develop a hallmark shoulder that was first modeled by Champagne and co-workers.

These CF pigs also develop the hallmark phenotype of lung disease [ 23] and have led to a better understanding of the underlying causes of CF in humans.

Rogers et al. [ 39] have identified that the CFTR gene knockout model of pig better mimics human pathology than mouse models as they fail to develop the hallmark pancreatic, lung and intestinal obstructions that occur in humans.

These two mouse models develop neuropathological hallmarks of AD differently in young adulthood.

However, Dresner-Pollak and coworkers indicated that reduced generation of osteoblasts has been found in bone marrow cell cultures obtained from IL-10 mice, and IL-10 mice develop the hallmarks of osteoporosis, that is, decreased bone mass, increased mechanical fragility, and suppressed bone formation [ 39].