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Finally, it may be possible to develop entry inhibitors, which stop the virus entering cells, or inhibitors of the 5′ capping process, which is required for viral replication.
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"The question is to what extent they can work and in what kinds of conditions," said Daniel Greenstein, director of postsecondary success strategies at the Bill & Melinda Gates Foundation, which has awarded $3 million in grants to develop entry-level and remedial courses and evaluate the viability of using so-called massive open online courses.
For cases where the CMV promoter might not be optimal for cDNA expression, we also developed Entry vectors that contain the human EF-1α promoter (Figure 2B).
In addition to assisting end user interface development, the same approach can be used to develop data entry mechanisms for medical devices and external systems.
We performed first-principles calculations based on the ab initio fragment molecular orbital method on dengue virus envelope protein with a hydrophobic ligand, octyl-β-d-glucose to develop an entry inhibitor.
The goal of this paper is to review efforts within the past five years to develop Ebolavirus entry inhibitors, placing an emphasis on chemical and structural aspects, and to identify opportunities for future development.
In all three states, UNICEF has supported analysis of the MAPEDIR data, and helped develop data entry and analysis software to ease transition of this function to district health offices.
In order to minimise data entry mistakes, we developed data entry forms that included range checks and missing value alerts.
In Mali, the decision to conduct a special active surveillance study was made 4 months prior to the campaign, leaving limited time for planning, particularly recruiting and training a data collection team, developing data entry screens and databases, pilot-testing data entry forms, and sensitizing clinicians to obtain the vaccination status of patients.
Even with passports, Cubans need visas to visit most places and as a developing country, entry requirements are strict.
DPF1 as an analog of gp120 containing the critical residues for CD4 binding might be useful for designing of HIV vaccines and developing HIV entry inhibitors.
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