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Among them, indole scaffolds have been found in most of the important synthetic drug molecules and paved a faithful way to develop effective targets.
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The success story of imatinib energized the cancer research community to identify molecular targets and develop effective targeting agents.
Lymphatics have been also implicated in the pathogenesis of idiopathic pulmonary fibrosis, lymphangioleiomyomatosis and metastatic cancer, representing a potential novel approach to develop effective target therapies of severe lung diseases [ 1, 13, 17, 20].
More precise specification of the effects that these individual domains of stigma have on the use and endorsement of voluntary counseling and testing (VCT) services is needed, in order to develop effective (targeted) stigma reduction strategies [ 5, 6].
Understanding the biophysical mechanisms of this cellular process is essential from a bioengineering point of view since it will provide guidance for developing effective targeted drug delivery therapies.
The purpose of this hypothesis testing is to detect dangerous zones of initial loads in pathogens in order to develop effective therapeutic targets in preclinical trials.
The variability in definitions and measures used in health literacy research has limited the ability to compare studies and advance the field to develop effective interventions targeting population groups with low health literacy [ 45, 46].
There is a particular need to develop effective interventions targeting economically disadvantaged patients with HF. 8 Results from our previously published Heart failure Adherence and Retention Trial (HART) suggested that patients with an annual income
Therefore, there is an urgent need to develop effective therapeutic approaches targeting highly heterogeneous pancreatic cancer cells and tumor microenvironments.
Efforts are now underway to develop effective antioxidant compounds targeted to mitochondria [17], [18].
9 Hence, to create a durable clinical response, it is very important to develop effective treatments that target and eliminate CSC.
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