While most people who are exposed to nonlethal levels of carbon monoxide fully recover, about 10percentt of those who are exposed to the gas, which is tasteless, colorless and odorless, develop delayed neurological and behavioral problems like memory loss and behavior change.
Infusion of PACAP1 38 provokes immediate headache in 11 out of 12 migraine patients, 7 of these patients develop delayed migraine attacks.
With respect to the postoperative CRP levels or the number of leukocytes, it was not possible to distinguish patients who would develop delayed complications and those who would not.
If patients with elevated PCT levels are at higher risk to develop delayed complications despite an initially uneventful postoperative course, PCT could be involved in the decision-making process for further therapy concepts.
Aneurysmal subarachnoid hemorrhage (SAH) is associated with high morbidity and mortality, but currently no single clinical method or ancillary test can reliably predict which subset of patients will develop delayed cerebral ischemia (DCI).
It is difficult to predict who will develop delayed sequelae; however, advanced age, loss of consciousness while poisoned, and initial neurological abnormalities may increase the chance of developing delayed symptoms.
Disrupted autoregulation may predict which patients will finally develop delayed infarction [ 106].
According to the literature, 21% of aSAH survivors, who do not develop vasospasm, develop delayed ischemic injury and only 20%30%% of those who develop delayed vasospasm suffer from delayed ischemic injury [ 150].
However, 0.2 40% of the survivors develop delayed neuropsychiatric sequelae (DNS) within 2 4 weeks after this pseudo recovery [ 4, 5].
Despite received various forms of treatments, forty percent of survivors develop delayed encephalopathy after a lucid interval from a few weeks up to months from the acute poisoning.
