Exact(8)
Instead, he says, researchers will have to uncover all of Plasmodium's routes into the cell and develop combination vaccines.
This randomised phase II study has shown that it is feasible to develop combination chemotherapy regimens incorporating weekly docetaxel for advanced oesophagogastric cancer.
Below, we will discuss the main effector pathways of KRAS and current approaches to develop combination therapies targeting these KRAS-effector pathways.
It may be more appropriate to develop combination therapeutic strategies to prevent metastasis rather than attempting to limit progression of established disease.
If we are to use these agents in the best way and, most critically, if we are to develop combination regimens that build on their efficacy, it is vital to identify who to treat using predictive biomarkers and with what dose and schedule, as determined by pharmacodynamic biomarkers.
Given the remarkable impact of anti-VEGF strategies on near-term patient outcomes, one strategy for managing a potential trade-off between the positive vascular outcomes and longer-term neuronal risk may be to develop combination treatments for neovascular conditions that include neuroprotectants.
Similar(51)
He bought a company Dr. Klug had founded and worked with him and researchers like Carl O. Pabo to improve the technique and develop combinations of zinc fingers to match any sequence of DNA letters.
Many companies are trying to develop combinations of pills — similar to those used to treat H.I.V. — that would eradicate the virus without the need for interferon.
However, in order to satisfy the regulatory requirements, it will be necessary to develop combinations of mechanism-based tests that can be carried out quickly.
Our data provide a rationale to develop combinations of mAbs for human H5N1 prophylaxis and therapeutics.
It also allows more 'breathing room' or capacity to develop combinations of these agents.
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