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In order to develop assays to more fully explore the potential heterogeneity of gene expression in RPCs, two ISH methods were used to examine expression, with an initial test using a probe for Cyclin D1, the gene expressed in the highest percentage of RPCs profiled.
To identify suitable genes, develop assays and establish their sensitivity, tests were carried out comparing responses of cultured T-lymphocytes from normal controls and an AT case.
The development of single nucleotide polymorphisms (SNPs) provides the opportunity to develop assays that are gene specific and often functionally relevant.
Hence, it is necessary to develop assays capable of discriminating between the two infections.
The guide was then used to develop assays for 11 known and novel human genetic polymorphisms.
EPA says it has taken so long in part because scientists had to develop assays for endocrine disruption.
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Part of this involves developing assays for assessing the activity of new anticancer compounds.
We developed assays for parasite-specific antibody responses in the medium ground finch (Geospiza fortis) (see Methods).
We developed assays for HPyV6, HPyV7, and HPyV9 using Primer Express software (Applied Biosystems, Carlsbad, CA, USA) (Table 1).
TECAN HOLDING, -- Hombrechtikon, Switzerland, a maker of liquid sample processors in the world, agreed to buy the closely held Gamera Bioscience Corp., Boston, which develops assays used to analyze samples, for $10 million.
The newly developed assays enable us to detect 1.1 CFU/100 g infant formula.
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