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In this paper we describe, develop and interrogate such an executable model of the gp130/JAK/STAT signalling pathway [ 12] using the Narrative Language approach and explore its predictions by in silico experimentation.
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Multiple hypotheses are being tested by developing and interrogating rodent models and rodent and human cell culture systems to characterize the molecular basis of mammary gland development over the life span.
Additionally, a search pattern was developed and used to interrogate the Rattus_norvegicus.RGSC3.1.nov.dna_rm.contig.fa.gz archive obtained from the Ensembl FTP resource [ 36].
The data obtained were normalized using in-house developed statistical method and interrogated by multivariate approaches.
Using methods developed to interrogate both assembled and unassembled sequences, we characterized and quantified TEs across three AS and three ECM species, including the AS outgroup Volvariella volvacea.
To store, integrate, display, and interrogate the data, we developed a platform based on Django, a python web framework (http://www.ncbi.nlm.nih.gov/genome/viruses/).nih.gov/genome/viruses/
A cell-free system was developed to interrogate the regulation and synthesis of FAs in E. coli through manipulation of the substrate, cofactors, allosteric regulators and enzyme level (Liu et al., 2010).
A Perl script was developed to interrogate the database and to identify associations between non-contiguous regions of the Arabidopsis genome that are linked by a number of disjoined mate-pair mappings and thus produce a list of cognate B. rapa BAC clones that might contain discontinuities.
To meet this need, we developed Glaucoma Discovery Platform (GDP), an online environment to visualize and interrogate large and complex expression datasets in a user-friendly manner.
Ultimately, bioinformatics needs to develop methods that interrogate the genome in the clinic and allow physicians to use personalized medicine in their daily practice.
A number of different structural and computational methods have been developed to interrogate these amino acid networks.
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CEO of Professional Science Editing for Scientists @ prosciediting.com