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We develop a tolerance to the effects of caffeine that reduces caffeine's effectiveness.
Addicts develop a tolerance to its euphoric effects and describe themselves as normalized by it, their cravings satisfied.
To protect himself, Mithridates devised a concoction of over fifty toxins which he sampled daily to develop a tolerance to all poisons.
And you can develop a tolerance to them, causing you to take larger and larger doses to get the same effect.
Individual susceptibility to arsenic poisoning varies widely; some persons have been known to develop a tolerance to doses that would kill others.
"This is certainly a risk, although when it's used appropriately, it's easy to avoid complications through monitoring and by gradually increasing the dose as patients develop a tolerance to its respiratory effects," Dr. Dahl said.
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There is no way of developing a tolerance to arsenic through eating small regular doses.
"Just as a drug user develops a tolerance and needs larger doses to achieve the same effect, so too have we developed a tolerance to amazing events," the survey notes.
Chris is uncomfortable about the normalisation of aggressive content: "I developed a tolerance to the videos I was watching.
"The cyanide provides no injury to the caterpillars themselves, because they long ago developed a tolerance to it," said Dr. Thomas Tobin, professor of pharmacology and toxicology at the Gluck Center.
It meant that his diabetes was so out of control that his body had developed a tolerance to big spikes in blood sugar.
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