Sentence examples for develop a mechanistic understanding of from inspiring English sources

To develop a mechanistic understanding of Nematostella development, several functional approaches have been established including morpholino-based gene knockdowns and gene overexpression [2], [10], [11].

Advances in inducible gene expression and knockdown, CRISPR/Cas9 technology, and fluorescent labeling of genetically modified cells offer the opportunity to test the roles of diverse adhesion systems and to develop a mechanistic understanding of how cell adhesion regulates development and cancer.

To develop a mechanistic understanding of surface reactions, e.g. surface complex formation, the pH-dependent ligand species distribution and the complex formation in solution need to be considered.

It is important to develop a mechanistic understanding of the underlying phenomena that will help suggest ways to control the drug release from a polymer hydrogel.

Work in multiple laboratories is underway to develop a mechanistic understanding of tDCS effects on different forms of learning and to optimize stimulation protocols.

Remotely sensed information on the spatial extent and intensity of forest disturbance would be extremely useful for managers and ecologists in attempts to develop a mechanistic understanding of forest degradation and the processes of forest disturbance [7, 8].

Since parameters including dislocation density, activation energy (Q) and work-hardening index (n) can play important roles in developing a mechanistic understanding of DSA, efforts have been made to evaluate them.

This paper focuses on developing a mechanistic understanding of the process of multiple nucleation bursts leading to the formation of multiple generations (or populations) of γ′ precipitates with different size distributions, during the continuous cooling of a commercially used nickel base superalloy.

Developing a mechanistic understanding of the ability of soluble Aβ to interfere with synaptic plasticity, and in particular the stable, translation-dependent forms of plasticity that are thought to mediate LTM, could yield important insights into the pathophysiology of AD. mTOR-mediated protein synthesis is important for long-lasting forms of synaptic plasticity and memory [34].

Also, the most parsimonious model is not always the most useful model for developing a mechanistic understanding of the system.

Attaining a thorough understanding of Hh signaling is of vital importance for developing a mechanistic understanding of congenital abnormalities and diseases.