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To develop a mechanistic understanding of Nematostella development, several functional approaches have been established including morpholino-based gene knockdowns and gene overexpression [2], [10], [11].
Advances in inducible gene expression and knockdown, CRISPR/Cas9 technology, and fluorescent labeling of genetically modified cells offer the opportunity to test the roles of diverse adhesion systems and to develop a mechanistic understanding of how cell adhesion regulates development and cancer.
It is important to develop a mechanistic understanding of the underlying phenomena that will help suggest ways to control the drug release from a polymer hydrogel.
Work in multiple laboratories is underway to develop a mechanistic understanding of tDCS effects on different forms of learning and to optimize stimulation protocols.
He studies natural diversity within and between plant species both in the field and in controlled environments, and he hopes to develop a mechanistic understanding or plant performance to conserve natural plant populations and to improve agricultural productivity and sustainability.
To develop a mechanistic understanding of surface reactions, e.g. surface complex formation, the pH-dependent ligand species distribution and the complex formation in solution need to be considered.
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The researchers will focus on developing a mechanistic understanding of how Azithromycin reshapes the gut microbiome, and how this altered microbiome state affects the host.
In particular, he is interested in developing a mechanistic understanding of physiologic systems, and in formulating appropriately chosen computational physiologic models for improved patient care.
Since parameters including dislocation density, activation energy (Q) and work-hardening index (n) can play important roles in developing a mechanistic understanding of DSA, efforts have been made to evaluate them.
This paper focuses on developing a mechanistic understanding of the process of multiple nucleation bursts leading to the formation of multiple generations (or populations) of γ′ precipitates with different size distributions, during the continuous cooling of a commercially used nickel base superalloy.
In particular, Dr. Heldt is interested in developing a mechanistic understanding of physiologic systems, and in formulating appropriately chosen computational physiologic models for improved patient care.
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