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Mutations in desmoplakin can result in devastating skin blistering diseases and arrhythmogenic right ventricular cardiomyopathy, a heart muscle disorder associated with ventricular arrhythmias, heart failure, and sudden death.
Buruli ulcer (BU) caused by Mycobacterium ulcerans is a devastating skin disease [ 1].
In fact, hundreds of tissue biomarkers are available in clinical laboratories for diagnosing melanoma and determining the prognosis and mutation status of this devastating skin disease.
MU is the agent responsible for Buruli ulcer (BU), a devastating skin disease with great health and socio-economic consequences in tropical and subtropical countries.
Human onchocerciasis is a neglected tropical parasitic disease caused by Onchocerca volvulus (O. volvulus) that may result in devastating skin and eye morbidity.
From a public health perspective, MU is the agent responsible for Buruli ulcer (BU), a devastating skin disease with great health and socio-economic consequences in tropical and subtropical countries (WHO, 2008).
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At the city's Broadgreen Hospital, Alisha Lawler knows just how devastating a skin cancer diagnosis can be.
Mycobacterium ulcerans (M. ulcerans) causes a devastating necrotising infection of skin tissue leading to progressive ulceration.
Although cryotherapy may be beneficial in treating acute and chronic phases of soft tissue injury, inappropriate use can lead to devastating complications such as full thickness skin necrosis and neuropathy.
Subsequent formation and deposition of chromatin-anti-chromatin complexes, primarily in the skin and kidneys, elicits devastating local inflammation [ 9, 10].
Vitiligo is the most frequent depigmentation disorder of the skin and is cosmetically and psychologically devastating.
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