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Spinal cord injuries (SCI) are among the most devastating pathologies of CNS, leading to partial or complete loss of respiratory, autonomic and sensory-motor functions [1].
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The vast majority of neurological disorders falls into the group of devastating pathology and takes place in the cerebral arteries which are called cerebrovascular accident (CVA) or stroke [ 72].
Acute brain injuries such as stroke, trauma, and haemorrhage, and chronic neurodegenerative diseases, including Alzheimer's and Parkinson's diseases, are devastating conditions with pathologies that are exacerbated by inflammation and IL-1.
The pathology of devastating lung diseases, including lung cancers, is likely in part due to dysregulation and dysfunction of lung stem cells.
Huntington's pathology is a devastating inherited neurodegenerative disease clinically characterized by involuntary movements, cognitive decline, emotional changes and dementia.
The collision between the politics of H.I.V./AIDS and the pathology of infectious disease was devastating then; there are signs now that a similar conflict may threaten public health in the midst of the current global TB epidemic — with implications that extend well beyond that one disease.
As stated earlier, this pathology can be a cosmetically devastating physical deformity, causing social isolation and depression.
Second, the pathology of injectional anthrax is especially devastating (11, 12 ).
This approach holds considerable significance to treat CNS pathology in GLD, MLD and possibly other devastating storage diseases and warrants validation in large animals before being considered for clinical evaluation.
Quietly devastating.
Devastating, even.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com