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The current crisis of confidence is just the latest, broadest and potentially most devastating manifestation of that alienation.
These mechanisms suggest novel therapeutic targets for the management or prevention of the most devastating manifestation of heart disease, sudden cardiac death (SCD).
Tuberculous meningitis is the most devastating manifestation of tuberculosis.
Neurodegeneration is a devastating manifestation in the majority of >50 LSDs.
Critical limb ischaemia, usually caused by atherosclerotic plaques blocking the blood vessels, is a common and devastating manifestation of peripheral arterial disease.
Oxidative stress in the brain is highly prevalent in many neurodegenerative disorders including lysosomal storage disorders, in which neurodegeneration is a devastating manifestation.
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responsible for devastating clinical manifestations.
The disease presents clinically with a broad range of manifestations including skeletal destruction, immune suppression and end-organ sequelae with devastating complications for patients and their quality of life.
Quietly devastating.
Devastating, even.
Just devastating.
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