But when you're a company as big as Google, even minor changes like this can have large, even devastating, impacts in niche communities.
In Veneto, the freshly re-elected governor, Luca Zaia, has ordered all local authorities to remove migrant housing and other dwellings from areas close to tourist destinations, saying their presence would have a "devastating" impact on tourism in the region around Venice.
Demographic changes, including (a) the projected increase in population of 388 million for a total of 1,186 million by 2020 (b) rapid urbanisation resulting in half the population living in urban areas by 2020, (c) the devastating impact of HIV/AIDS (d) the changes in age structure of the population and (e) population movements, including those resulting from conflicts and natural disasters.
Howell Raines wisely describes the devastating impact of George C. Wallace's racist politics in Alabama (Editorial Observer, April 26).
A search for transcription factor binding sites within the PINK1 5' region [ 29] identified PPARγ and numerous myogenic transcription factor binding sites (see Additional file 2), supporting the robust expression of PINK1 in mitochondria rich striated muscle and the recently demonstrated and devastating impact of loss of PINK1 expression in Drosophila flight muscle [ 21].
In a recent radio broadcast, Prime Minister Narendra Modi acknowledged the devastating impact of climate change on India.
A proposal to temporarily restore long-term unemployment benefits, which have been been cut for 1.5 million jobseekers, with devastating impacts across the country, have stalled in the Senate after opposition from Republicans.
This is important given the high reported incidence of both OH and falls in older adults, and devastating impact of fall-related injury on quality of life for those affected [ 2, 3].
In the long run, malnutrition and infectious diseases may accumulate devastating impacts on the human capital of poor plasma donors and undermine governmental poverty alleviation efforts.
