Scientists are furiously searching for a way of picking up the devastating disorder in those first stages, in the hope that prompt treatment might slow its progression and perhaps someday, with new treatments, stop it altogether.
Cerebral palsy, estimated to occur in three out of 1,000 newborns, is a lifelong, often devastating disorder caused by infection or reduced oxygen to the brain before, during or immediately after birth.
The devastating disorder causes a decline in motor, cognitive and psychiatric functions.
Although transcriptional modifications, excitotoxicity, protein aggregation and loss of normal function of huntingtin, have been hypothesized to be responsible for the symptoms in patients [1], HD remains a devastating disorder with no effective treatment.
Cytokine research is of tremendous interest to those with the devastating disorder.
The result is a sharper focus on the nature and course of this devastating disorder as well as a sounder foundation for the assessment of various treatments.
Similarly, a devastating disorder called glutaric aciduria was traced to an amino acid problem, with a treatment devised to reduce the risk of brain damage.
Alzheimer's disease (AD) is a devastating disorder that strikes 1 in 10 Americans over the age of 65, and almost half of all Americans over 85 years old.
The therapeutic potential of these findings needs to be carefully evaluated in the near future, hopefully resulting in new treatment options for this devastating disorder.
The writer describes the conflict between insurers and the Hutchinson Center in the Center's effort to use marrow transplantation for a devastating disorder of the immune system called scleroderma.
In this Review, we summarise the current understanding of CADASIL, a devastating disorder that also serves as a model for the more common forms of subcortical ischaemic strokes and pure vascular dementia.
