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It also poses a devastating challenge to traditional linear planning approaches and to our ways of working.
A further scan on Friday may tell whether the leg, shattered in the devastating challenge by PSV's Hector Moreno back in September, is healing in such a way that his season need not be over.
Overall, the book, which follows Pussy's flight to London and his mistaken arrest in connection with a pub bombing, is a devastating challenge to the macho terrorist culture of Northern Ireland: "McCabe's latest may be the most successful book yet to be born out of violence," concluded the New York Times Book Review.
They'll do a good job at this with a hefty content and marketing budget, but with limited distribution (online only) and a "new music" format it's unlikely to be a devastating challenge to existing UK radio stations.
It is clear, however, that health care is an often devastating challenge confronting millions of Hispanics.
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Allegations of policy perjury made by Federal prosecutors and a state judge are devastating challenges to the integrity of the Police Department that must be answered with utmost speed.
The 21st century has brought devastating challenges to this worldview: the Sept. 11 attacks and the catastrophic occupations in the Middle East; the financial crisis and the end of the belief that endless progress was possible for many.
Man of the match: Justin Harrison The 6ft 9in Harrison, who was 19 before he took up rugby union, started with devastating challenges against the Lions throw-in to the middle and tail of the line-out - the effect of which was to undermine the Lions' line-out confidence throughout.> Furthermore, almost every Lions re-start ball seemed to go into his safe arms.
It would be wonderful if they could marshal that inspiration to find answers to some of the devastating challenges humanity currently faces: climate change and its attendant crises, dwindling energy supplies, genocide, brutality against women, terrorism, rapacious corporate greed.
If the reports are true, at long last someone -- most likely someone within the religious leadership in Iran has prevailed upon a president who has brought his nation to the brink of a devastating defensive challenge from Israel, not known for a bashful reticence to defend her people.
But the rate of change of computational power is so much faster than the rate at which human institutions can adapt -- let alone the rate at which the human species evolves -- that we will face devastating existential challenges to human civilization.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com