Sentence examples for detrimental expression from inspiring English sources

Ideally, vectors for gene transfer into human cells should be capable of transgene expression without replication or detrimental expression of viral genes.

Together, these results demonstrate that hnRNP C safeguards the transcriptome from aberrant and potentially detrimental expression of cryptic exons, most particularly those originating from Alu elements.

Based on these findings we propose a model to explain the role of additive expression in generation of heterosis for GY in maize by the compensation of fixed detrimental expression levels in parents.

Based on the finding that the majority of the analyzed heterosis-associated genes were addtitively expressed, we propose a model referring to the influence of cis-regulatory variation on heterosis for GY by the compensation of fixed detrimental expression levels in parents.

This fitness loss can be caused by particular functions carried on the plasmid which are detrimental upon expression in the new host (e.g. regulatory proteins interfering with the global gene expression network), or by proteins expressed from plasmid which have a direct phenotypic effect (e.g. antibiotic resistance) (Nguyen et al., 1989).

This would shed further light on the detrimental (increased expression of CXCR3-ligating chemokines, Th1 recruitment and associated pathology) versus beneficial (optimal Th1 responses required for macrophage activation and mycobacterial control) effects of early neutrophil influx in TB pathogenesis.

It is not clear why this small, 5 bp region between the CUP1 promoter's transcriptional start site and the start of the open reading frame would be detrimental for expression in yeast.

The culture of chondrocytes proved detrimental to COL9A1 expression, with significant loss of expression.

These observations argue that even 'normal' tau may be detrimental when its expression becomes elevated.

However, it was detrimental if the expression of inhibitory molecule persisted during the stage of immunosuppression.

This is potentially detrimental for the expression value of the probe set summarized from individual probe-level data.