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Uptake and reduction by microorganisms is another detoxification process for Cr VI), although it is limited by the ability of resistant bacteria striving in contaminated water to rapidly extrude Cr VI).
Mussatto, Santos and Roberto [ 21] evaluated the detoxification process for a rice straw hemicellulosic hydrolysate using activated carbon adsorption and observed that, the xylose concentrations were reduced by 4% to 18%.
The possible explanation for this effect could be that the increase in the formation of liver lipid peroxidation in prallethrin-intoxicated animals acted as a signal to maintain lower levels of antioxidant enzymes (SOD, CAT, and GST) in order to enhance the triggering of the detoxification process for the pyrethroid.
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Detoxification process of cellular inhibitors including furfural is essential for production of bio-based chemicals from lignocellulosic biomass.
Also, to the best of our knowledge, this is the first study to explore the chemical profile of aconitum roots after treating by two forms of Shodhana (an ancient Ayurveda detoxification process) and for quantitation of the toxic alkaloids before and after processing.
A pictorial representation of the detoxification strategy used is shown in Figure 2, and the LC-MS spectra of marker compounds are shown in Figure 3. Figure 2 Representation of Shodhana and TCM detoxification process applied for selected Aconitum species (A) Drug treated with cow urine (B) Drug boiled in cow milk (C) Pre-soaked drug subjected to decoction with water.
Among the other potential roles, it has been demonstrated that efflux pumps are important for detoxification processes of intracellular metabolites, bacterial virulence in both animal and plant hosts, cell homeostasis and intercellular signal trafficking [ 8].
Whether TaMDR1 thus has a similar relevance for the detoxification process as can be suggested for TaPDR1, still needs to be proven in a further study.
During this detoxification process, the monomers required for the formation of metal nanoparticles are generated which subsequently undergo nucleation and form nanoparticles. Intracellular accumulation of metals occurs with metabolically active cells (Wang and Chen 2009).
The accumulation of nanoparticles in the liver may be due to Kupffer cells intake for detoxification process [ 26].
Another problem during the detoxification process is the requirement for additional operation units, which significantly increases the production cost [ 12- 15].
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