Glucuronidation is a major detoxification pathway in vertebrates.
Glyoxalases are involved in a ubiquitous detoxification pathway.
Methylation of inorganic arsenic (InAs) has generally been considered to be a detoxification pathway.
Luciferase reporter assays indicate that nanosilver treatment induces activation of the ARE detoxification pathway through nuclear respiratory factor 2 (Nrf 2), as opposed to nuclear respiratory factor 1 (Nrf1), while suppressing the XRE detoxification pathway through the AhR.
Nevertheless, our data, through supporting a function for PXR in BC formation, reinforce the conclusion that PXR exerts pleiotropic roles in cellular metabolism and physiology, apart from that initially devoted to drug detoxification pathway regulation47,48,49.
Mice convert a higher portion of the parent compound to highly carcinogenic 1,2,3,4-diepoxybutane 1,2,3,4-diepoxybutanetion pathwhileia conjugathen with glutathione is more prominent in rats (Thornton-Manning et al., 1995).
Quindolone derivatives, designed to target the malaria parasite digestive vacuole and heme detoxification pathway, have been synthesized by reaction with 2-chloro-N,N-diethylethanamine.
Humus can serve as a detoxification pathway by assuming the role taken by biomolecules in the metal toxicity mechanisms discussed above.
No correlation was identified between melphalan sensitivity and the GST/glutathione cellular detoxification pathway.
The following two up-regulated proteins thioredoxin peroxidase (TPX) and ascorbate peroxidase (APX) involved in plant detoxification pathway.
The red cross represents native formaldehyde detoxification pathway (formaldehyde to CO2) is blocked by knocking out formaldehyde dehydrogenase gene frmA.
