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This clearly implies that the vigorous biosorption of a particular heavy metal (Cr2+) by P. ostreatus may not necessarily be followed by the detoxification levels of Cr2+ into the clean ranges of pollution rating.
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As the cell lines exhibit a similar chemosensitivity pattern to that observed in clinical practice, these differences in glutathione and detoxification enzyme levels may prove to be important indicators of intrinsic drug resistance often seen in patients with non-small cell lung cancer.
In 2-week-old cultures, expression of detoxification genes reached levels close to or higher than those measured in freshly isolated hepatocytes.
CAT is an important antioxidant enzyme involved in H2O2 detoxification [ 35], levels decreased significantly in WT plants but only slightly changed in TaNAC29-overexpression lines following salt stress (Fig. 6f), indicating that TaNAC29-overexpression lines scavenged more H2O2.
And marine ecologist Charles Peterson of the University of North Carolina in Chapel Hill notes that recent studies have shown elevated levels of detoxification enzymes in ducks and otters in the Knight Island area.
Therefore, changes in the levels of detoxification proteins and stress-responsive genes may collectively contribute to the increased salt tolerance in these genetically modified organisms.
Similar geographical variations in expression levels between detoxification genes have been observed in other mosquito vectors, such as An.
The increase in ROS levels activates detoxification mechanisms that act as antioxidants and reduce the synthesis of ROS [ 49].
We also found that, in general, low levels of detoxification and stress related genes are expressed in pupae, adult males and larvae than in adult females.
It is now apparent that the development of herbicide resistance in several weeds is the result of enhanced detoxification associated with elevated levels of CYP activity.
Increased levels of detoxification enzymes such as epoxide hydrolase, glucuronosyl transferase, and sulfotransferase are the likely one of the mechanisms for chemoprevention of PEITC.
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