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The comparison between the two strains was aimed at determining whether the selected genes were differentially expressed in the arthritis-susceptible DA rat versus the arthritis-resistant congenic DA.
This 'proof of principle' study represents an important initial step in determining whether the selected measures of activity and the analytic strategy proposed could be applied to larger datasets (obtained from a single large-scale study or pooled data from several independent studies).
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For every SNP showing association with disease (p-value <0.005) that has recently undergone positive selection (|iHS| >2.2), we determined whether the selected allele within the SNP is associated with susceptibility to disease versus protection from disease (Table 1 and Table S1).
The lack of fit is designed to determine whether the selected model is adequate to describe the observed data or whether a more complicated model should be used.
We first determined whether the selected drug resistant cell lines show cross-resistance to different drugs.
Moreover, we also aimed to determine whether the selected socio-demographic and clinical variables were predictive of variability in the HRQoL scores over time.
Moreover, we also aimed to determine whether the selected socio-demographic and clinical characteristics were predictive of variability in the HRQoL scores over time.
Finally, we performed epitope binning experiments to determine whether the selected DARPins bind to overlapping or to different epitopes on their respective target protein.
To determine whether the selected governmental health facilities of Baglung district satisfy the conditions for safe injections in terms of staff training, availability of sterile injectable equipment and their proper disposal after use and 2. To assess knowledge and attitudes of healthcare workers in these health facilities with regard to injection safety.
They asked the EPA to take this into consideration as it determines whether to select asbestos among the initial 10 chemicals for risk evaluation" under the changes to the Toxic Substances Control Act.
As the first step, we determined whether the three selected miRs were expressed in myogenic cells, such as primary mouse satellite cells and C2C12 cell lines, and in skeletal and heart muscle tissues obtained from five-month-old wt mice.
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