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"The phase-one trials are successful in that they did what they were supposed to do in terms of determining toxicity levels".
But Seiji Oshumi, director of the Cetacean Research Institute, said his researchers performed more than 100 different scientific tests on the whales, including determining toxicity levels of internal organs and stomach contents, which he said required the whales to be killed.
Thus, protein interactions that alter aggregate conformation could play an important role in determining toxicity.
Understanding the complex signaling processes between these different cell types is crucial in determining toxicity potential.
These findings are likely to indicate a role for peptide conformation in determining toxicity.
The oxidative stress response is one of the most determining toxicity factors.
Similar(46)
Elderly status (age > 65 years), PS > 2, and/or comorbidities represent major features determining toxicities and limiting quality of life of treated patients, thus limiting indication of sorafenib.
For determining toxicities of vinblastine, vincristine and doxorubicin, 20 embryos were incubated in glass petri dishes with 10 mL test solutions and two to three replicates per treatment.
This indicates it is mostly the G content that determines toxicity.
Dalzell, D. J. B. et al. A comparison of five rapid direct toxicity assessment methods to determine toxicity of pollutants to activated sludge.
The normalized relative transpiration (NRT) rate of weeping willows was used to determine toxicity.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com