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SG, IT, and HM participated in determining the study design and interpreting the data, and helped to draft the manuscript.
This period often entails processes such as building a team, understanding the system in which the PFA will occur, defining the objectives and process measures of the study, determining the study plan, developing PFA documents and ensuring that necessary equipment is available, identifying and training key personnel, and briefing the staff.
One study included 481 subjects with a long follow-up and repeated measurements, and it used repeated brief telephone interviews for determining the study outcome, and the authors reported greater cognitive decline in subjects with a low Aβ1-42/Aβ1-40 at baseline [ 64].
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This approach contrasts with traditional models of clinical research in which researchers determine the study's design.
As Eberhart et al. (1999) demonstrate, the choice of performance metrics significantly determines the study results.
Open image in new window Fig. 1 Algorithm used to determine the study cohort.
In case of disagreement based on abstract, the full-text article was obtained to determine the study eligibility.
The racial information determines the study data that the program uses, since the consensus in the forensic community is that dental development varies widely according to ethnicity.
JF, MM and SH determined the study design.
First, the results were used to shape the research question and to determine the study design.
A second limitation is the use of RDS to determine the study population.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com