Sentence examples for determining the potency and from inspiring English sources
Structure activity relationship studies indicated that the shape of the linking group and the shape of the substituent at the distal benzene ring play key roles in determining the potency and the selectivity of PPAR subtype transactivation.
Structure activity relationship studies indicated that the shape of the linker moiety and the nature of the substituent at the distal benzene ring play key roles in determining the potency and selectivity of PPAR subtype transactivation.
Structure activity relationship studies indicated that the substituent at the α-position of the carboxyl group plays a key role in determining the potency and the selectivity for PPAR transactivation.
There is evidence, however, to support the belief that the dicationic state of 82+ also plays a significant role in determining the potency and pharmacokinetic behavior observed during the screening against cancer cells.
The results show that high titers of vaccine-induced anti-V3 Abs in plasma determine the potency and breadth of neutralization, as well as the rate of transduction of Abs to mucosal tissues, where they can play a role in preventing HIV-1 infection.
Further, in addition to the need of technical and outcome standardization, rigorous randomized controlled trials and long term follow up data are required to determine the potency and oncological risk.
In the well-characterized TRIM5α post-entry restriction, the TRIM5α B30.2(PRYSPRY) determines the potency and specificity of restriction.
Kinobead-based profiling enables access to a sizable fraction of the expressed trypanosome kinome, which can be used to determine the potency and selectivity of kinase inhibitors in cell extracts by means of a multiplexed competition binding assay.
Mutational studies that replaced the native N-terminal residue of LF with known N-end rule stabilizing or destabilizing residues confirmed that the N-terminal residue plays a significant role in determining the potency of LT for cultured cells and experimental animals.
This suggests that factors other than CD86 expression are involved in determining the potency of DC in an MLR, and implies that irradiation may compromise DC/T-cell interactions during immune priming.
