Sentence examples for determining the conformation of from inspiring English sources
In the present study we sought to gain insight into the mechanism of end recognition by determining the conformation of αβ-tubulin recognized by TOG2 and by testing whether cooperative TOG:αβ-tubulin interactions contributed to polymerase activity.
It is suggested that the conformation of the diazo compound in the crystal determines the conformation of the carbene intermediate which is predisposed for a conformationally stereospecific 1,2-H shift.
A number of examples discussed in this review demonstrate how this methodology can be used to determine the conformation of membrane-associated peptides, their position along the bilayer normal, and their state of aggregation.
The structure of the triple mutant aL2-6E7S10G shows the FR-H1 backbone conformations predicted for this amino acid combination, which is distinctly different from the structure of the w.t, thus supporting our hypothesis that these residues determine the conformation of this segment.
Protein ligand docking can be defined as a search algorithm with a scoring function, whose aim is to determine the conformation of the ligand and the receptor with the lowest energy.
In addition to analysis by chemical crosslinking of the recombinant proteins, monoclonal antibody binding was used to determine the conformation of the recombinant soluble HA.
While peptide binding affinities, as measured by fluorescence polarization, correlate with the relative proportion of extended peptide conformation, these results suggest a model where all three residues C-terminal to the phosphotyrosine determine the conformation of the bound phosphopeptide.
It will be interesting in the future to determine the conformation of AlHV-1 genome in infected CD8+ cells and to unravel the roles of AlHV-1 ORF73 in the pathogenesis of WD-MCF.
