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The way in which the innate and adaptive immune system initially recognizes and deals with replicating virus could be decisive in determining outcome of infection, as this might heavily influence the kinetics of viral clearance [1], [2], [3].
The balance between proinflammatory IFNγ and downmodulatory IL10 has been shown to be critical in determining outcome of mycobacterial infections [31], and the IFNγ (5d) /IL10 (2d) ratio induced in response to mycobacterial antigens has been shown to be to be an indicator of disease severity in tuberculosis [32].
35 Duration of submersion is the predominant factor in determining outcome of drowning.
Route of delivery is another important variable determining outcome of cell-based trials.
As PD CA125 increases during peritoneal inflammation, we wished to determine whether measuring PD CA125 during peritonitis provided additional information in determining outcome of peritonitis.
Our results provide important new data supporting the role of HLA-A*03 as an important driver of protective immune responses in HCV and offers insight into the formidable interplay between host and virus in determining outcome of infection.
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Finally, different understory responses between sites suggests that pretreatment conditions are important for determining outcomes of pinyon-juniper removal treatments.
To assess whether progesterone elevation is the only factor in determining outcomes of in vitro fertilization (IVF).
To determine outcome of cataract surgery in severely subluxated traumatic cataracts.
To determine outcome of children born with isolated gastroschisis (no extra-gastrointestinal congenital abnormalities).
These were stored for later correlating histopathologic responses and viral load with the subsequently determined outcome of infection.
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